The short answer
Esomeprazole has no single cash price. Your total depends on the exact product, pharmacy, quantity, insurance, and offer. The CMS numbers below are pharmacy acquisition benchmarks—not patient prices.
Published pharmacy prices · Cash pay
Esomeprazole prices at Cost Plus Drugs
Compare available sources with prescription price search
Selected generic tablet and capsule offers from one mail-order pharmacy. These are dated pharmacy estimates, separate from CMS acquisition benchmarks. We have not compared the whole market or verified your insurance benefit.
Checked . Use these observations only before ; confirm the price at checkout.
No current in-stock price observations are available for the selected products. Check the pharmacy directly.
| Exact product / quantity | Medication + dispensing | Shipping | Total with shipping |
|---|---|---|---|
| Esomeprazole Magnesium 20mgCapsule · 30 capsules · Generic | $5.84Medication $0.84 Dispensing $5.00 | Included in total; not itemized | $11.09Source-reported total |
| Esomeprazole Magnesium 20mgCapsule · 60 capsules · Generic | $6.68Medication $1.68 Dispensing $5.00 | Confirm with pharmacy | Not availableShipping not supplied |
| Esomeprazole Magnesium 20mgCapsule · 90 capsules · Generic | $7.52Medication $2.52 Dispensing $5.00 | Confirm with pharmacy | Not availableShipping not supplied |
| Esomeprazole Magnesium 40mgCapsule · 30 capsules · Generic | $5.86Medication $0.86 Dispensing $5.00 | Included in total; not itemized | $11.11Source-reported total |
| Esomeprazole Magnesium 40mgCapsule · 60 capsules · Generic | $6.72Medication $1.72 Dispensing $5.00 | Confirm with pharmacy | Not availableShipping not supplied |
| Esomeprazole Magnesium 40mgCapsule · 90 capsules · Generic | $7.58Medication $2.58 Dispensing $5.00 | Confirm with pharmacy | Not availableShipping not supplied |
Listed products were marked in stock when checked. A displayed shipping total is for one medication; do not add it repeatedly when comparing a combined order. Delivery eligibility, taxes if applicable, and the final checkout amount must be confirmed with the pharmacy.
Product links open the pharmacy’s listing to confirm the offer. This selection excludes packaged bottles, granule boxes, and products whose quantity units we cannot safely match.
Check current Cost Plus Drugs listings · How we collect pharmacy prices
International price references
United Kingdom: NHS medication reimbursement reference (per pack) (GBP) · France: France BDPM public pack prices (EUR) · Sweden: Sweden TLV pharmacy selling prices (SEK) · Denmark: Denmark Medicinpriser retail prices (DKK). Amounts retain each source’s pricing basis and currency. Individual reimbursement and product equivalence are not calculated.
Before you compare Esomeprazole
Match the prescription product and packaging, including delayed-release wording. Retail over-the-counter shelf prices may describe a different package.
Esomeprazole acquisition-cost reference
One representative NDC per description. Values retain five decimal places so low per-unit costs do not round to zero. EA means “each”; confirm the dispensing unit and package with your pharmacist.
Snapshot retrieved 2026-10-29. Individual record dates appear below.
| Product description / NDC | NADAC per unit | Unit | As of |
|---|---|---|---|
| esomeprazole dr 10 mg packetNDC 13668054894 · Generic | $4.65131 | EA | |
| esomeprazole dr 2.5 mg packetNDC 13668054694 · Generic | $5.31495 | EA | |
| esomeprazole dr 20 mg packetNDC 13668054994 · Generic | $3.62194 | EA | |
| esomeprazole dr 40 mg packetNDC 13668055094 · Generic | $4.36735 | EA | |
| esomeprazole dr 5 mg packetNDC 13668054794 · Generic | $4.58949 | EA | |
| esomeprazole mag dr 20 mg capNDC 00378235077 · Generic | $0.13966 | EA | |
| esomeprazole mag dr 40 mg capNDC 00378235177 · Generic | $0.12792 | EA |
Original CMS dataset · Download this reference as JSON · How we select records
CMS lists the underlying NADAC data as public domain. This designation applies to the CMS data, not the accompanying RxCompare articles or site design.
Acquisition benchmark history
Observed CMS acquisition costs for pharmacies, not prices patients pay. We compare only the same NDC, description, classification, and unit. No retail savings are inferred. Archive, downloads, and history methodology.
esomeprazole dr 10 mg packet · $0.00000 per EA change since 2026-10-21
NDC 13668054894 · EA · 14 source dates. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-01-28 | 2026-10-19 | $6.38446 | JSON |
| 2026-02-25 | 2026-10-19 | $6.20485 | JSON |
| 2026-03-25 | 2026-10-19 | $6.19998 | JSON |
| 2026-04-29 | 2026-10-19 | $6.19832 | JSON |
| 2026-05-27 | 2026-10-19 | $5.97047 | JSON |
| 2026-06-24 | 2026-10-19 | $5.72585 | JSON |
| 2026-07-29 | 2026-10-19 | $5.55895 | JSON |
| 2026-08-26 | 2026-10-19 | $5.22590 | JSON |
| 2026-09-16 | 2026-09-22 | $5.22590 | JSON |
| 2026-09-30 | 2026-10-19 | $4.96363 | JSON |
| 2026-10-07 | 2026-10-07 | $4.96363 | JSON |
| 2026-10-14 | 2026-10-15 | $4.96363 | JSON |
| 2026-10-21 | 2026-10-22 | $4.65131 | JSON |
| 2026-10-28 | 2026-10-29 | $4.65131 | JSON |
esomeprazole dr 2.5 mg packet · $0.00000 per EA change since 2026-10-21
NDC 13668054694 · EA · 14 source dates. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-01-28 | 2026-10-19 | $6.79979 | JSON |
| 2026-02-25 | 2026-10-19 | $6.83760 | JSON |
| 2026-03-25 | 2026-10-19 | $6.74550 | JSON |
| 2026-04-29 | 2026-10-19 | $6.60790 | JSON |
| 2026-05-27 | 2026-10-19 | $6.31711 | JSON |
| 2026-06-24 | 2026-10-19 | $6.13874 | JSON |
| 2026-07-29 | 2026-10-19 | $5.92274 | JSON |
| 2026-08-26 | 2026-10-19 | $5.69727 | JSON |
| 2026-09-16 | 2026-09-22 | $5.69727 | JSON |
| 2026-09-30 | 2026-10-19 | $5.49156 | JSON |
| 2026-10-07 | 2026-10-07 | $5.49156 | JSON |
| 2026-10-14 | 2026-10-15 | $5.49156 | JSON |
| 2026-10-21 | 2026-10-22 | $5.31495 | JSON |
| 2026-10-28 | 2026-10-29 | $5.31495 | JSON |
esomeprazole dr 20 mg packet · $0.00000 per EA change since 2026-10-21
NDC 13668054994 · EA · 14 source dates. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-01-28 | 2026-10-19 | $5.77549 | JSON |
| 2026-02-25 | 2026-10-19 | $5.75122 | JSON |
| 2026-03-25 | 2026-10-19 | $5.67089 | JSON |
| 2026-04-29 | 2026-10-19 | $5.47006 | JSON |
| 2026-05-27 | 2026-10-19 | $5.31835 | JSON |
| 2026-06-24 | 2026-10-19 | $5.29353 | JSON |
| 2026-07-29 | 2026-10-19 | $5.14536 | JSON |
| 2026-08-26 | 2026-10-19 | $4.50731 | JSON |
| 2026-09-16 | 2026-09-22 | $4.50731 | JSON |
| 2026-09-30 | 2026-10-19 | $4.00136 | JSON |
| 2026-10-07 | 2026-10-07 | $4.00136 | JSON |
| 2026-10-14 | 2026-10-15 | $4.00136 | JSON |
| 2026-10-21 | 2026-10-22 | $3.62194 | JSON |
| 2026-10-28 | 2026-10-29 | $3.62194 | JSON |
esomeprazole dr 40 mg packet · $0.00000 per EA change since 2026-10-21
NDC 13668055094 · EA · 14 source dates. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-01-28 | 2026-10-19 | $6.79960 | JSON |
| 2026-02-25 | 2026-10-19 | $6.64570 | JSON |
| 2026-03-25 | 2026-10-19 | $6.42421 | JSON |
| 2026-04-29 | 2026-10-19 | $5.62867 | JSON |
| 2026-05-27 | 2026-10-19 | $5.07992 | JSON |
| 2026-06-24 | 2026-10-19 | $4.65437 | JSON |
| 2026-07-29 | 2026-10-19 | $4.53041 | JSON |
| 2026-08-26 | 2026-10-19 | $4.38966 | JSON |
| 2026-09-16 | 2026-09-22 | $4.38966 | JSON |
| 2026-09-30 | 2026-10-19 | $4.17167 | JSON |
| 2026-10-07 | 2026-10-07 | $4.17167 | JSON |
| 2026-10-14 | 2026-10-15 | $4.17167 | JSON |
| 2026-10-21 | 2026-10-22 | $4.36735 | JSON |
| 2026-10-28 | 2026-10-29 | $4.36735 | JSON |
esomeprazole dr 5 mg packet · $0.00000 per EA change since 2026-10-21
NDC 13668054794 · EA · 14 source dates. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-01-28 | 2026-10-19 | $6.86262 | JSON |
| 2026-02-25 | 2026-10-19 | $6.64522 | JSON |
| 2026-03-25 | 2026-10-19 | $6.40362 | JSON |
| 2026-04-29 | 2026-10-19 | $6.21689 | JSON |
| 2026-05-27 | 2026-10-19 | $6.08106 | JSON |
| 2026-06-24 | 2026-10-19 | $5.98247 | JSON |
| 2026-07-29 | 2026-10-19 | $5.76019 | JSON |
| 2026-08-26 | 2026-10-19 | $5.46654 | JSON |
| 2026-09-16 | 2026-09-22 | $5.46654 | JSON |
| 2026-09-30 | 2026-10-19 | $5.00536 | JSON |
| 2026-10-07 | 2026-10-07 | $5.00536 | JSON |
| 2026-10-14 | 2026-10-15 | $5.00536 | JSON |
| 2026-10-21 | 2026-10-22 | $4.58949 | JSON |
| 2026-10-28 | 2026-10-29 | $4.58949 | JSON |
esomeprazole mag dr 20 mg cap · $0.00000 per EA change since 2026-10-21
NDC 00378235077 · EA · 14 source dates. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-01-28 | 2026-10-19 | $0.16597 | JSON |
| 2026-02-25 | 2026-10-19 | $0.16432 | JSON |
| 2026-03-25 | 2026-10-19 | $0.16577 | JSON |
| 2026-04-29 | 2026-10-19 | $0.16903 | JSON |
| 2026-05-27 | 2026-10-19 | $0.16281 | JSON |
| 2026-06-24 | 2026-10-19 | $0.16044 | JSON |
| 2026-07-29 | 2026-10-19 | $0.15673 | JSON |
| 2026-08-26 | 2026-10-19 | $0.15327 | JSON |
| 2026-09-16 | 2026-09-22 | $0.15327 | JSON |
| 2026-09-30 | 2026-10-19 | $0.14458 | JSON |
| 2026-10-07 | 2026-10-07 | $0.14458 | JSON |
| 2026-10-14 | 2026-10-15 | $0.14458 | JSON |
| 2026-10-21 | 2026-10-22 | $0.13966 | JSON |
| 2026-10-28 | 2026-10-29 | $0.13966 | JSON |
esomeprazole mag dr 40 mg cap · $0.00000 per EA change since 2026-10-21
NDC 00378235177 · EA · 14 source dates. Missing observations are not interpolated.
| Source date | First retrieved | USD per EA | Snapshot |
|---|---|---|---|
| 2026-01-28 | 2026-10-19 | $0.14339 | JSON |
| 2026-02-25 | 2026-10-19 | $0.14145 | JSON |
| 2026-03-25 | 2026-10-19 | $0.13883 | JSON |
| 2026-04-29 | 2026-10-19 | $0.13636 | JSON |
| 2026-05-27 | 2026-10-19 | $0.13164 | JSON |
| 2026-06-24 | 2026-10-19 | $0.12657 | JSON |
| 2026-07-29 | 2026-10-19 | $0.12037 | JSON |
| 2026-08-26 | 2026-10-19 | $0.11802 | JSON |
| 2026-09-16 | 2026-09-22 | $0.11802 | JSON |
| 2026-09-30 | 2026-10-19 | $0.12181 | JSON |
| 2026-10-07 | 2026-10-07 | $0.12181 | JSON |
| 2026-10-14 | 2026-10-15 | $0.12181 | JSON |
| 2026-10-21 | 2026-10-22 | $0.12792 | JSON |
| 2026-10-28 | 2026-10-29 | $0.12792 | JSON |
Get a price for your prescription
- Match the label. Write down the full product name, strength, dosage form, and quantity. Ask the pharmacy about the package if you are unsure.
- Ask for separate totals. Get the cash price, insurance price, and any discount offer for the same fill.
- Include required fees. Add delivery or membership costs that are not already included in the quote.
- Compare and confirm. Use your actual quotes in the calculator and ask your plan about the effect on your benefit.
A question to bring to the counter
“Could you check the cash total and my insurance cost for my prescribed Esomeprazole, with the same strength, form, and quantity? Are there any extra fees, and is this the final price for this fill?”
Common questions
How much does Esomeprazole cost without insurance?
RxCompare does not have a live retail quote for Esomeprazole. Request the cash total for your prescribed strength, form, and quantity from a pharmacy. The table on this page is an acquisition-cost reference, not an amount you can expect to pay.
Can I compare different Esomeprazole strengths?
Use the exact prescribed product for a fair price comparison. Do not change strength, form, or release type based on a benchmark; ask your clinician or pharmacist about medication changes.
Why is my pharmacy quote different from this table?
The table reports a dated national acquisition benchmark for one representative NDC per description. Your pharmacy may stock another package or manufacturer, and retail pricing includes more than acquisition cost.
Sources & further reading
Source links checked 2026-09-22. Cost information only; this content has not been clinically reviewed.