The short answer

To check levothyroxine costs without insurance, request a pharmacy cash quote for your exact prescribed product and quantity, then compare eligible discount totals including fees. Selected pharmacy estimates, when available below, have their own check and expiry times. Your total depends on the exact product, pharmacy, quantity, insurance, and offer. The CMS numbers below are pharmacy acquisition benchmarks—not patient prices.

Published pharmacy prices · Cash pay

Levothyroxine prices at Cost Plus Drugs

Compare available sources with prescription price search

Selected generic tablet and capsule offers from one mail-order pharmacy. These are dated pharmacy estimates, separate from CMS acquisition benchmarks. We have not compared the whole market or verified your insurance benefit.

Checked . Use these observations only before ; confirm the price at checkout.

Cost Plus Drugs · USD · quantity means tablets or capsules, not days supplied
Exact product / quantityMedication + dispensingShippingTotal with shipping
Levothyroxine 25mcgTablet · 30 tablets · Generic$5.91Medication $0.91
Dispensing $5.00
Included in total; not itemized$11.16Source-reported total
Levothyroxine 25mcgTablet · 60 tablets · Generic$6.82Medication $1.82
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 25mcgTablet · 90 tablets · Generic$7.73Medication $2.73
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 50mcgTablet · 30 tablets · Generic$5.91Medication $0.91
Dispensing $5.00
Included in total; not itemized$11.16Source-reported total
Levothyroxine 50mcgTablet · 60 tablets · Generic$6.83Medication $1.83
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 50mcgTablet · 90 tablets · Generic$7.74Medication $2.74
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 75mcgTablet · 30 tablets · Generic$5.95Medication $0.95
Dispensing $5.00
Included in total; not itemized$11.20Source-reported total
Levothyroxine 75mcgTablet · 60 tablets · Generic$6.89Medication $1.89
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 75mcgTablet · 90 tablets · Generic$7.84Medication $2.84
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 88mcgTablet · 30 tablets · Generic$5.94Medication $0.94
Dispensing $5.00
Included in total; not itemized$11.19Source-reported total
Levothyroxine 88mcgTablet · 60 tablets · Generic$6.88Medication $1.88
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 88mcgTablet · 90 tablets · Generic$7.83Medication $2.83
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 100mcgTablet · 30 tablets · Generic$6.09Medication $1.09
Dispensing $5.00
Included in total; not itemized$11.34Source-reported total
Levothyroxine 100mcgTablet · 60 tablets · Generic$7.18Medication $2.18
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 100mcgTablet · 90 tablets · Generic$8.28Medication $3.28
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 112mcgTablet · 30 tablets · Generic$6.04Medication $1.04
Dispensing $5.00
Included in total; not itemized$11.29Source-reported total
Levothyroxine 112mcgTablet · 60 tablets · Generic$7.07Medication $2.07
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 112mcgTablet · 90 tablets · Generic$8.11Medication $3.11
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 125mcgTablet · 30 tablets · Generic$6.08Medication $1.08
Dispensing $5.00
Included in total; not itemized$11.33Source-reported total
Levothyroxine 125mcgTablet · 60 tablets · Generic$7.15Medication $2.15
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 125mcgTablet · 90 tablets · Generic$8.23Medication $3.23
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 137mcgTablet · 30 tablets · Generic$6.08Medication $1.08
Dispensing $5.00
Included in total; not itemized$11.33Source-reported total
Levothyroxine 137mcgTablet · 60 tablets · Generic$7.17Medication $2.17
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 137mcgTablet · 90 tablets · Generic$8.25Medication $3.25
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 150mcgTablet · 30 tablets · Generic$6.09Medication $1.09
Dispensing $5.00
Included in total; not itemized$11.34Source-reported total
Levothyroxine 150mcgTablet · 60 tablets · Generic$7.18Medication $2.18
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 150mcgTablet · 90 tablets · Generic$8.28Medication $3.28
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 175mcgTablet · 30 tablets · Generic$6.39Medication $1.39
Dispensing $5.00
Included in total; not itemized$11.64Source-reported total
Levothyroxine 175mcgTablet · 60 tablets · Generic$7.77Medication $2.77
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 175mcgTablet · 90 tablets · Generic$9.16Medication $4.16
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 200mcgTablet · 30 tablets · Generic$6.41Medication $1.41
Dispensing $5.00
Included in total; not itemized$11.66Source-reported total
Levothyroxine 200mcgTablet · 60 tablets · Generic$7.82Medication $2.82
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 200mcgTablet · 90 tablets · Generic$9.22Medication $4.22
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 300mcgTablet · 30 tablets · Generic$5.96Medication $0.96
Dispensing $5.00
Included in total; not itemized$11.21Source-reported total
Levothyroxine 300mcgTablet · 60 tablets · Generic$6.92Medication $1.92
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied
Levothyroxine 300mcgTablet · 90 tablets · Generic$7.87Medication $2.87
Dispensing $5.00
Confirm with pharmacyNot availableShipping not supplied

Listed products were marked in stock when checked. A displayed shipping total is for one medication; do not add it repeatedly when comparing a combined order. Delivery eligibility, taxes if applicable, and the final checkout amount must be confirmed with the pharmacy.

Product links open the pharmacy’s listing to confirm the offer. Discuss product or manufacturer changes with your pharmacist before switching. This selection excludes packaged bottles, granule boxes, and products whose quantity units we cannot safely match.

Check current Cost Plus Drugs listings · How we collect pharmacy prices

Programs to check for this medication

Eligibility and exact product matching matter. These resources do not establish that your prescription qualifies.

International price references

Canada: Ontario Drug Benefit Formulary (CAD) · United Kingdom: NHS medication reimbursement reference (per pack) (GBP) · France: France BDPM public pack prices (EUR) · Sweden: Sweden TLV pharmacy selling prices (SEK) · Denmark: Denmark Medicinpriser retail prices (DKK). Amounts retain each source’s pricing basis and currency. Individual reimbursement and product equivalence are not calculated.

Before you compare Levothyroxine

Copy the exact product name and strength, including mcg, from your label. Ask your pharmacist before changing the manufacturer or product.

Get a levothyroxine quote for the exact product

Write down the full product name, dosage form, strength including “mcg,” and quantity. If a brand is specified, include it. A search for “levothyroxine price” can lead to a quote for a different product from the one you take.

MedlinePlus advises discussing a levothyroxine brand change with your doctor or pharmacist. If another pharmacy offers a different product or manufacturer, ask your pharmacist to check the proposed fill before treating it as an equivalent price comparison.

Can you quote my exact levothyroxine product, strength in mcg, form, and quantity without insurance? Would filling it here involve any product or manufacturer change that I should discuss with my pharmacist?

Sources: MedlinePlus: Levothyroxine product changes.

Compare refill costs while keeping the product consistent

Ask for separate cash, discount, and insurance totals where applicable. Record the exact product beside each price, then include delivery and required membership fees. If two quotes use different names or forms, leave the comparison open until the pharmacist confirms what each quote covers.

For a longer supply, confirm the prescription permits it and compare the same number of days. Keep the cost-per-day calculation separate from the amount due today. Do not change your prescribed dose or schedule to fit a cheaper offer.

Compare different supply lengths

Check a price change against your previous receipt

Product descriptions12
Pricing unitsEA
SourceCMS NADAC

Levothyroxine acquisition-cost reference

One representative NDC per description. Values retain five decimal places so low per-unit costs do not round to zero. EA means “each”; confirm the dispensing unit and package with your pharmacist.

Snapshot retrieved 2026-10-29. Individual record dates appear below.

Levothyroxine CMS NADAC records · not retail prices
Product description / NDCNADAC per unitUnitAs of
levothyroxine 100 mcg tabletNDC 00378180910 · Generic$0.04954EA
levothyroxine 112 mcg tabletNDC 00378181110 · Generic$0.05794EA
levothyroxine 125 mcg tabletNDC 00378181310 · Generic$0.05754EA
levothyroxine 137 mcg tabletNDC 00378182310 · Generic$0.06326EA
levothyroxine 150 mcg tabletNDC 00378181510 · Generic$0.05665EA
levothyroxine 175 mcg tabletNDC 00378181710 · Generic$0.07481EA
levothyroxine 200 mcg tabletNDC 00378181910 · Generic$0.08494EA
levothyroxine 25 mcg tabletNDC 00378180010 · Generic$0.03517EA
levothyroxine 300 mcg tabletNDC 00378182177 · Generic$0.10949EA
levothyroxine 50 mcg tabletNDC 00378180310 · Generic$0.04006EA
levothyroxine 75 mcg tabletNDC 00378180510 · Generic$0.04681EA
levothyroxine 88 mcg tabletNDC 00378180710 · Generic$0.04760EA

Original CMS dataset · Download this reference as JSON · How we select records

CMS lists the underlying NADAC data as public domain. This designation applies to the CMS data, not the accompanying RxCompare articles or site design.

Acquisition benchmark history

Observed CMS acquisition costs for pharmacies, not prices patients pay. We compare only the same NDC, description, classification, and unit. No retail savings are inferred. Archive, downloads, and history methodology.

levothyroxine 100 mcg tablet · $0.00000 per EA change since 2026-10-21

NDC 00378180910 · EA · 14 source dates. Missing observations are not interpolated.

2026-01-28 to 2026-10-28 · range $0.04954–$0.05499 per EA. Vertical scale fits the observed range.
Recorded acquisition benchmarks for levothyroxine 100 mcg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-01-282026-10-19$0.05499JSON
2026-02-252026-10-19$0.05259JSON
2026-03-252026-10-19$0.05258JSON
2026-04-292026-10-19$0.05322JSON
2026-05-272026-10-19$0.05205JSON
2026-06-242026-10-19$0.05092JSON
2026-07-292026-10-19$0.05161JSON
2026-08-262026-10-19$0.05073JSON
2026-09-162026-09-22$0.05073JSON
2026-09-302026-10-19$0.04972JSON
2026-10-072026-10-07$0.04972JSON
2026-10-142026-10-15$0.04972JSON
2026-10-212026-10-22$0.04954JSON
2026-10-282026-10-29$0.04954JSON
levothyroxine 112 mcg tablet · $0.00000 per EA change since 2026-10-21

NDC 00378181110 · EA · 14 source dates. Missing observations are not interpolated.

2026-01-28 to 2026-10-28 · range $0.05794–$0.06476 per EA. Vertical scale fits the observed range.
Recorded acquisition benchmarks for levothyroxine 112 mcg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-01-282026-10-19$0.06476JSON
2026-02-252026-10-19$0.06335JSON
2026-03-252026-10-19$0.06320JSON
2026-04-292026-10-19$0.06363JSON
2026-05-272026-10-19$0.06343JSON
2026-06-242026-10-19$0.06164JSON
2026-07-292026-10-19$0.06035JSON
2026-08-262026-10-19$0.05894JSON
2026-09-162026-09-22$0.05894JSON
2026-09-302026-10-19$0.05879JSON
2026-10-072026-10-07$0.05879JSON
2026-10-142026-10-15$0.05879JSON
2026-10-212026-10-22$0.05794JSON
2026-10-282026-10-29$0.05794JSON
levothyroxine 125 mcg tablet · $0.00000 per EA change since 2026-10-21

NDC 00378181310 · EA · 14 source dates. Missing observations are not interpolated.

2026-01-28 to 2026-10-28 · range $0.05694–$0.06435 per EA. Vertical scale fits the observed range.
Recorded acquisition benchmarks for levothyroxine 125 mcg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-01-282026-10-19$0.06435JSON
2026-02-252026-10-19$0.06065JSON
2026-03-252026-10-19$0.06093JSON
2026-04-292026-10-19$0.06176JSON
2026-05-272026-10-19$0.06056JSON
2026-06-242026-10-19$0.05838JSON
2026-07-292026-10-19$0.05694JSON
2026-08-262026-10-19$0.05705JSON
2026-09-162026-09-22$0.05705JSON
2026-09-302026-10-19$0.05704JSON
2026-10-072026-10-07$0.05704JSON
2026-10-142026-10-15$0.05704JSON
2026-10-212026-10-22$0.05754JSON
2026-10-282026-10-29$0.05754JSON
levothyroxine 137 mcg tablet · $0.00000 per EA change since 2026-10-21

NDC 00378182310 · EA · 14 source dates. Missing observations are not interpolated.

2026-01-28 to 2026-10-28 · range $0.06235–$0.07463 per EA. Vertical scale fits the observed range.
Recorded acquisition benchmarks for levothyroxine 137 mcg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-01-282026-10-19$0.07463JSON
2026-02-252026-10-19$0.07013JSON
2026-03-252026-10-19$0.06694JSON
2026-04-292026-10-19$0.06499JSON
2026-05-272026-10-19$0.06426JSON
2026-06-242026-10-19$0.06295JSON
2026-07-292026-10-19$0.06235JSON
2026-08-262026-10-19$0.06273JSON
2026-09-162026-09-22$0.06273JSON
2026-09-302026-10-19$0.06388JSON
2026-10-072026-10-07$0.06388JSON
2026-10-142026-10-15$0.06388JSON
2026-10-212026-10-22$0.06326JSON
2026-10-282026-10-29$0.06326JSON
levothyroxine 150 mcg tablet · $0.00000 per EA change since 2026-10-21

NDC 00378181510 · EA · 14 source dates. Missing observations are not interpolated.

2026-01-28 to 2026-10-28 · range $0.05665–$0.07024 per EA. Vertical scale fits the observed range.
Recorded acquisition benchmarks for levothyroxine 150 mcg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-01-282026-10-19$0.07024JSON
2026-02-252026-10-19$0.06752JSON
2026-03-252026-10-19$0.06715JSON
2026-04-292026-10-19$0.06736JSON
2026-05-272026-10-19$0.06547JSON
2026-06-242026-10-19$0.06350JSON
2026-07-292026-10-19$0.06251JSON
2026-08-262026-10-19$0.05968JSON
2026-09-162026-09-22$0.05968JSON
2026-09-302026-10-19$0.05858JSON
2026-10-072026-10-07$0.05858JSON
2026-10-142026-10-15$0.05858JSON
2026-10-212026-10-22$0.05665JSON
2026-10-282026-10-29$0.05665JSON
levothyroxine 175 mcg tablet · $0.00000 per EA change since 2026-10-21

NDC 00378181710 · EA · 14 source dates. Missing observations are not interpolated.

2026-01-28 to 2026-10-28 · range $0.07347–$0.10563 per EA. Vertical scale fits the observed range.
Recorded acquisition benchmarks for levothyroxine 175 mcg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-01-282026-10-19$0.10563JSON
2026-02-252026-10-19$0.09701JSON
2026-03-252026-10-19$0.08783JSON
2026-04-292026-10-19$0.08105JSON
2026-05-272026-10-19$0.07988JSON
2026-06-242026-10-19$0.07998JSON
2026-07-292026-10-19$0.08048JSON
2026-08-262026-10-19$0.07654JSON
2026-09-162026-09-22$0.07654JSON
2026-09-302026-10-19$0.07347JSON
2026-10-072026-10-07$0.07347JSON
2026-10-142026-10-15$0.07347JSON
2026-10-212026-10-22$0.07481JSON
2026-10-282026-10-29$0.07481JSON
levothyroxine 200 mcg tablet · $0.00000 per EA change since 2026-10-21

NDC 00378181910 · EA · 14 source dates. Missing observations are not interpolated.

2026-01-28 to 2026-10-28 · range $0.07831–$0.08494 per EA. Vertical scale fits the observed range.
Recorded acquisition benchmarks for levothyroxine 200 mcg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-01-282026-10-19$0.08263JSON
2026-02-252026-10-19$0.08128JSON
2026-03-252026-10-19$0.07969JSON
2026-04-292026-10-19$0.08116JSON
2026-05-272026-10-19$0.08002JSON
2026-06-242026-10-19$0.08056JSON
2026-07-292026-10-19$0.07831JSON
2026-08-262026-10-19$0.08017JSON
2026-09-162026-09-22$0.08017JSON
2026-09-302026-10-19$0.08099JSON
2026-10-072026-10-07$0.08099JSON
2026-10-142026-10-15$0.08099JSON
2026-10-212026-10-22$0.08494JSON
2026-10-282026-10-29$0.08494JSON
levothyroxine 25 mcg tablet · $0.00000 per EA change since 2026-10-21

NDC 00378180010 · EA · 14 source dates. Missing observations are not interpolated.

2026-01-28 to 2026-10-28 · range $0.03506–$0.03841 per EA. Vertical scale fits the observed range.
Recorded acquisition benchmarks for levothyroxine 25 mcg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-01-282026-10-19$0.03841JSON
2026-02-252026-10-19$0.03758JSON
2026-03-252026-10-19$0.03749JSON
2026-04-292026-10-19$0.03796JSON
2026-05-272026-10-19$0.03733JSON
2026-06-242026-10-19$0.03624JSON
2026-07-292026-10-19$0.03587JSON
2026-08-262026-10-19$0.03568JSON
2026-09-162026-09-22$0.03568JSON
2026-09-302026-10-19$0.03506JSON
2026-10-072026-10-07$0.03506JSON
2026-10-142026-10-15$0.03506JSON
2026-10-212026-10-22$0.03517JSON
2026-10-282026-10-29$0.03517JSON
levothyroxine 300 mcg tablet · $0.00000 per EA change since 2026-10-21

NDC 00378182177 · EA · 14 source dates. Missing observations are not interpolated.

2026-01-28 to 2026-10-28 · range $0.09986–$0.11556 per EA. Vertical scale fits the observed range.
Recorded acquisition benchmarks for levothyroxine 300 mcg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-01-282026-10-19$0.11321JSON
2026-02-252026-10-19$0.11556JSON
2026-03-252026-10-19$0.10976JSON
2026-04-292026-10-19$0.11351JSON
2026-05-272026-10-19$0.11260JSON
2026-06-242026-10-19$0.10841JSON
2026-07-292026-10-19$0.10674JSON
2026-08-262026-10-19$0.09986JSON
2026-09-162026-09-22$0.09986JSON
2026-09-302026-10-19$0.10428JSON
2026-10-072026-10-07$0.10428JSON
2026-10-142026-10-15$0.10428JSON
2026-10-212026-10-22$0.10949JSON
2026-10-282026-10-29$0.10949JSON
levothyroxine 50 mcg tablet · $0.00000 per EA change since 2026-10-21

NDC 00378180310 · EA · 14 source dates. Missing observations are not interpolated.

2026-01-28 to 2026-10-28 · range $0.04006–$0.04736 per EA. Vertical scale fits the observed range.
Recorded acquisition benchmarks for levothyroxine 50 mcg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-01-282026-10-19$0.04706JSON
2026-02-252026-10-19$0.04610JSON
2026-03-252026-10-19$0.04588JSON
2026-04-292026-10-19$0.04736JSON
2026-05-272026-10-19$0.04623JSON
2026-06-242026-10-19$0.04483JSON
2026-07-292026-10-19$0.04323JSON
2026-08-262026-10-19$0.04062JSON
2026-09-162026-09-22$0.04062JSON
2026-09-302026-10-19$0.04073JSON
2026-10-072026-10-07$0.04073JSON
2026-10-142026-10-15$0.04073JSON
2026-10-212026-10-22$0.04006JSON
2026-10-282026-10-29$0.04006JSON
levothyroxine 75 mcg tablet · $0.00000 per EA change since 2026-10-21

NDC 00378180510 · EA · 14 source dates. Missing observations are not interpolated.

2026-01-28 to 2026-10-28 · range $0.04612–$0.04954 per EA. Vertical scale fits the observed range.
Recorded acquisition benchmarks for levothyroxine 75 mcg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-01-282026-10-19$0.04954JSON
2026-02-252026-10-19$0.04850JSON
2026-03-252026-10-19$0.04697JSON
2026-04-292026-10-19$0.04924JSON
2026-05-272026-10-19$0.04892JSON
2026-06-242026-10-19$0.04882JSON
2026-07-292026-10-19$0.04763JSON
2026-08-262026-10-19$0.04633JSON
2026-09-162026-09-22$0.04633JSON
2026-09-302026-10-19$0.04612JSON
2026-10-072026-10-07$0.04612JSON
2026-10-142026-10-15$0.04612JSON
2026-10-212026-10-22$0.04681JSON
2026-10-282026-10-29$0.04681JSON
levothyroxine 88 mcg tablet · $0.00000 per EA change since 2026-10-21

NDC 00378180710 · EA · 14 source dates. Missing observations are not interpolated.

2026-01-28 to 2026-10-28 · range $0.04760–$0.05416 per EA. Vertical scale fits the observed range.
Recorded acquisition benchmarks for levothyroxine 88 mcg tablet
Source dateFirst retrievedUSD per EASnapshot
2026-01-282026-10-19$0.05372JSON
2026-02-252026-10-19$0.05355JSON
2026-03-252026-10-19$0.05347JSON
2026-04-292026-10-19$0.05416JSON
2026-05-272026-10-19$0.05353JSON
2026-06-242026-10-19$0.05219JSON
2026-07-292026-10-19$0.05247JSON
2026-08-262026-10-19$0.05015JSON
2026-09-162026-09-22$0.05015JSON
2026-09-302026-10-19$0.04947JSON
2026-10-072026-10-07$0.04947JSON
2026-10-142026-10-15$0.04947JSON
2026-10-212026-10-22$0.04760JSON
2026-10-282026-10-29$0.04760JSON

Get a price for your prescription

  1. Match the label. Write down the full product name, strength, dosage form, and quantity. Ask the pharmacy about the package if you are unsure.
  2. Ask for separate totals. Get the cash price, insurance price, and any discount offer for the same fill.
  3. Include required fees. Add delivery or membership costs that are not already included in the quote.
  4. Compare and confirm. Use your actual quotes in the calculator and ask your plan about the effect on your benefit.
Compare my Levothyroxine costs

A question to bring to the counter

“Could you check the cash total and my insurance cost for my prescribed Levothyroxine, with the same strength, form, and quantity? Are there any extra fees, and is this the final price for this fill?”

Common questions

Can I use a generic levothyroxine quote for a branded prescription?

Treat it as a different quote until your pharmacist checks your prescription and proposed product. Keep the exact name, strength, form, and quantity in the comparison, and discuss product changes with your care team.

How much does Levothyroxine cost without insurance?

Check the published pharmacy estimates above and request the final cash total for your prescribed strength, form, and quantity. The separate CMS table is an acquisition-cost reference, not an amount you can expect to pay.

Can I compare different Levothyroxine strengths?

Use the exact prescribed product for a fair price comparison. Do not change strength, form, or release type based on a benchmark; ask your clinician or pharmacist about medication changes.

Why is my pharmacy quote different from this table?

The table reports a dated national acquisition benchmark for one representative NDC per description. Your pharmacy may stock another package or manufacturer, and retail pricing includes more than acquisition cost.

Sources & further reading

Source links checked 2026-10-19. Cost information only; this content has not been clinically reviewed.